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Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

BACKGROUND: Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy. The aim of the study was to assess neurotoxicity of bupivacaine and liposome...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Markova, Liljana, Umek, Nejc, Horvat, Simon, Hadžić, Admir, Kuroda, Max, Pintarič, Tatjana Stopar, Mrak, Vesna, Cvetko, Erika
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367396/
https://ncbi.nlm.nih.gov/pubmed/32680505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02459-4
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