Extracellular vesicles from deciduous pulp stem cells recover bone loss by regulating telomerase activity in an osteoporosis mouse model

BACKGROUND: Systemic transplantation of stem cells from human exfoliated deciduous teeth (SHED) recovers bone loss in animal models of osteoporosis; however, the mechanisms underlying this remain unclear. Here, we hypothesized that trophic factors within SHED-releasing extracellular vesicles (SHED-E...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Sonoda, Soichiro, Murata, Sara, Nishida, Kento, Kato, Hiroki, Uehara, Norihisa, Kyumoto, Yukari N., Yamaza, Haruyoshi, Takahashi, Ichiro, Kukita, Toshio, Yamaza, Takayoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367365/
https://ncbi.nlm.nih.gov/pubmed/32680564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01818-0
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