Suppression of AKT-mTOR signal pathway enhances osteogenic/dentinogenic capacity of stem cells from apical papilla

BACKGROUND: Stem cells from apical papilla (SCAP) are a subpopulation of mesenchymal stem cells (MSCs) isolated from the apical papilla of the developing tooth root apex of human teeth. Because of their osteogenic/dentinogenic capacity, SCAP are considered as a source for bone and dentin regeneratio...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Tanaka, Yosuke, Sonoda, Soichiro, Yamaza, Haruyoshi, Murata, Sara, Nishida, Kento, Hama, Shion, Kyumoto-Nakamura, Yukari, Uehara, Norihisa, Nonaka, Kazuaki, Kukita, Toshio, Yamaza, Takayoshi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264601/
https://ncbi.nlm.nih.gov/pubmed/30486861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1077-9
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