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“Oil-soluble” reversed lipid nanoparticles for oral insulin delivery
BACKGROUND: In this study, we aimed to design a novel oral insulin delivery system, named “oil-soluble” reversed lipid nanoparticles (ORLN), in which a hydrophilic insulin molecule is encapsulated by a phospholipid (PC) shell and dissolved in oil to prevent the enzymatic degradation of insulin. ORLN...
Gespeichert in:
| Veröffentlicht in: | J Nanobiotechnology |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7367322/ https://ncbi.nlm.nih.gov/pubmed/32680576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00657-8 |
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