“Oil-soluble” reversed lipid nanoparticles for oral insulin delivery

BACKGROUND: In this study, we aimed to design a novel oral insulin delivery system, named “oil-soluble” reversed lipid nanoparticles (ORLN), in which a hydrophilic insulin molecule is encapsulated by a phospholipid (PC) shell and dissolved in oil to prevent the enzymatic degradation of insulin. ORLN...

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Bibliografiske detaljer
Udgivet i:J Nanobiotechnology
Main Authors: Wang, Tao, Shen, Liao, Zhang, Yadan, Li, Haiyan, Wang, Yongan, Quan, Dongqin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367322/
https://ncbi.nlm.nih.gov/pubmed/32680576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00657-8
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