Zinc finger protein ZFP36L1 inhibits influenza A virus through translational repression by targeting HA, M and NS RNA transcripts

ZFP36L1, a CCCH-type zinc finger protein, is an RNA-binding protein that participates in controlling cellular mRNA abundance and turnover by posttranscriptional regulation. Here, we demonstrated that ZFP36L1 has an important role in host defense against influenza A virus (IAV) infection. Overexpress...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Lin, Ren-Jye, Huang, Chih-Heng, Liu, Ping-Cheng, Lin, I-Chieh, Huang, Yu-Ling, Chen, An-Yu, Chiu, Hsin-Ping, Shih, Shin-Ru, Lin, Li-Hsiung, Lien, Shu-Pei, Yen, Li-Chen, Liao, Ching-Len
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
RNA and RNA-protein complexes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367194/
https://ncbi.nlm.nih.gov/pubmed/32556261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa458
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