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Dissemination of Ras(V12)-transformed cells requires the mechanosensitive channel Piezo

Dissemination of transformed cells is a key process in metastasis. Despite its importance, how transformed cells disseminate from an intact tissue and enter the circulation is poorly understood. Here, we use a fully developed tissue, Drosophila midgut, and describe the morphologically distinct steps...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lee, Jiae, Cabrera, Alejandra J. H., Nguyen, Cecilia M. T., Kwon, Young V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366633/
https://ncbi.nlm.nih.gov/pubmed/32678085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17341-y
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