Lymphovascular Invasion Is Associated with Mutational Burden and PD-L1 in Resected Lung Cancer

BACKGROUND: High tumor mutational burden (TMB) and PD-L1 expression are leading biomarkers in metastatic non-small cell lung cancer (NSCLC) and predict favorable response to checkpoint inhibitors. We sought to identify clinicopathologic characteristics associated with elevated TMB and PD-L1 expressi...

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Detalhes bibliográficos
Publicado no:Ann Thorac Surg
Main Authors: Mitchell, Kyle G., Negrao, Marcelo V., Parra, Edwin R., Li, Jun, Zhang, Jianhua, Dejima, Hitoshi, Vaporciyan, Ara A., Swisher, Stephen G., Weissferdt, Annikka, Antonoff, Mara B., Cascone, Tina, Roarty, Emily, Wistuba, Ignacio I., Heymach, John V., Gibbons, Don L., Zhang, Jianjun, Sepesi, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366360/
https://ncbi.nlm.nih.gov/pubmed/31550464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2019.08.029
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