Lymphovascular Invasion Is Associated with Mutational Burden and PD-L1 in Resected Lung Cancer

BACKGROUND: High tumor mutational burden (TMB) and PD-L1 expression are leading biomarkers in metastatic non-small cell lung cancer (NSCLC) and predict favorable response to checkpoint inhibitors. We sought to identify clinicopathologic characteristics associated with elevated TMB and PD-L1 expressi...

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Bibliografske podrobnosti
izdano v:Ann Thorac Surg
Main Authors: Mitchell, Kyle G., Negrao, Marcelo V., Parra, Edwin R., Li, Jun, Zhang, Jianhua, Dejima, Hitoshi, Vaporciyan, Ara A., Swisher, Stephen G., Weissferdt, Annikka, Antonoff, Mara B., Cascone, Tina, Roarty, Emily, Wistuba, Ignacio I., Heymach, John V., Gibbons, Don L., Zhang, Jianjun, Sepesi, Boris
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366360/
https://ncbi.nlm.nih.gov/pubmed/31550464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2019.08.029
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