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Synergistic Interaction of Histone Deacetylase 6- and MEK-Inhibitors in Castration-Resistant Prostate Cancer Cells

In spite of new knowledge on prostate cancer molecular landscape, this has been only partially translated to the therapeutic setting. The activation of Ras/Mitogen-activated protein kinase (MAPK) signaling plays an important role in progression of prostate cancer in which deregulation of histone dea...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Corno, Cristina, Arrighetti, Noemi, Ciusani, Emilio, Corna, Elisabetta, Carenini, Nives, Zaffaroni, Nadia, Gatti, Laura, Perego, Paola
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365948/
https://ncbi.nlm.nih.gov/pubmed/32754596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00610
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