Dynamic transcriptional responses to injury of regenerative and non-regenerative cardiomyocytes revealed by single-nucleus RNA sequencing

The adult mammalian heart is incapable of regeneration following injury. In contrast, the neonatal mouse heart can efficiently regenerate during the first week of life. The molecular mechanisms that mediate the regenerative response and its blockade in later life are not understood. Here, by single-...

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Bibliografske podrobnosti
izdano v:Dev Cell
Main Authors: Cui, Miao, Wang, Zhaoning, Chen, Kenian, Shah, Akansha M., Tan, Wei, Duan, Lauren, Sanchez-Ortiz, Efrain, Li, Hui, Xu, Lin, Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365574/
https://ncbi.nlm.nih.gov/pubmed/32220304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.02.019
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