Dynamic transcriptional responses to injury of regenerative and non-regenerative cardiomyocytes revealed by single-nucleus RNA sequencing

The adult mammalian heart is incapable of regeneration following injury. In contrast, the neonatal mouse heart can efficiently regenerate during the first week of life. The molecular mechanisms that mediate the regenerative response and its blockade in later life are not understood. Here, by single-...

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Publicat a:Dev Cell
Autors principals: Cui, Miao, Wang, Zhaoning, Chen, Kenian, Shah, Akansha M., Tan, Wei, Duan, Lauren, Sanchez-Ortiz, Efrain, Li, Hui, Xu, Lin, Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365574/
https://ncbi.nlm.nih.gov/pubmed/32220304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.02.019
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