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IGF1 gene is epigenetically activated in preterm infants with intrauterine growth restriction

BACKGROUND: IGF1 is a key molecule in the regulation of growth and metabolism. Low IGF1 secretion is known to cause growth restriction in childhood, as well as deregulated lipid metabolism, cardiovascular disease, and diabetes in adulthood. The IGF1 gene P2 promoter is highly methylated, resulting i...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Kantake, Masato, Ikeda, Naho, Nakaoka, Hirofumi, Ohkawa, Natsuki, Tanaka, Toshitaka, Miyabayashi, Kazuki, Shoji, Hiromichi, Shimizu, Toshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364555/
https://ncbi.nlm.nih.gov/pubmed/32678007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00901-w
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