Pharmacokinetic Effects of l-Tetrahydropalmatine on Ketamine in Rat Plasma by Ultraperformance Liquid Chromatography Tandem Mass Spectrometry

Male Sprague-Dawley rats (n = 18) were randomly divided into three groups: a saline group (20 mL/kg by gavage), a ketamine (KET) group (100 mg/kg by gavage), and a KET (the same routes and doses) combined with levo-tetrahydropalmatine (l-THP; 40 mg/kg by gavage) group (n = 6). Blood samples were acq...

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Detalles Bibliográficos
Publicado en:Biomed Res Int
Main Authors: Du, Yan, Su, Hongliang, Cao, Jie, Wei, Zhiwen, Wang, Yujin, Yun, Keming
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364195/
https://ncbi.nlm.nih.gov/pubmed/32724819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9259683
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