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Quercetin and Isoquercitrin Inhibiting Hepatic Gluconeogenesis Through LKB1-AMPKα Pathway

OBJECTIVE: To observe the impact of quercetin and isoquercitrin on gluconeogenesis in hepatocytes. METHODS: Mouse primary hepatocytes were cultured with lactic acid and pyruvic acid. After treatment with quercetin and isoquercitrin for 24 hours, the glucose concentration in the culture supernatant w...

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Publicat a:Acta Endocrinol (Buchar)
Autors principals: Chen, L., Shen, T., Zhang, C.P., Xu, B.L., Qiu, Y.Y., Xie, X.Y., Wang, Q., Lei, T.
Format: Artigo
Idioma:Inglês
Publicat: Acta Endocrinologica Foundation 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363997/
https://ncbi.nlm.nih.gov/pubmed/32685032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4183/aeb.2020.9
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