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Increased Dendritic Branching of and Reduced δ-GABA(A) Receptor Expression on Parvalbumin-Positive Interneurons Increase Inhibitory Currents and Reduce Synaptic Plasticity at Puberty in Female Mouse CA1 Hippocampus

Parvalbumin positive (PV+) interneurons play a pivotal role in cognition and are known to be regulated developmentally and by ovarian hormones. The onset of puberty represents the end of a period of optimal learning when impairments in synaptic plasticity are observed in the CA1 hippocampus of femal...

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Pubblicato in:Front Cell Neurosci
Autori principali: Shen, Hui, Kenney, Lindsay, Smith, Sheryl S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363981/
https://ncbi.nlm.nih.gov/pubmed/32733208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00203
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