A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and Their Differentiated Derivatives

Single-cell transcriptomic approaches have found molecular heterogeneities within populations of pluripotent stem cells (PSCs). A tool that tracks single-cell lineages and their phenotypes longitudinally would reveal whether heterogeneity extends beyond molecular identity. Hence, we generated a stab...

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Vydáno v:Stem Cell Reports
Hlavní autoři: El-Nachef, Danny, Shi, Kevin, Beussman, Kevin M., Martinez, Refugio, Regier, Mary C., Everett, Guy W., Murry, Charles E., Stevens, Kelly R., Young, Jessica E., Sniadecki, Nathan J., Davis, Jennifer
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363961/
https://ncbi.nlm.nih.gov/pubmed/32619493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.06.005
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