Rapid Crypt Cell Remodeling Regenerates the Intestinal Stem Cell Niche after Notch Inhibition

Intestinal crypts have great capacity for repair and regeneration after intestinal stem cell (ISC) injury. Here, we define the cellular remodeling process resulting from ISC niche interruption by transient Notch pathway inhibition in adult mice. Although ISCs were retained, lineage tracing demonstra...

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Bibliografiset tiedot
Julkaisussa:Stem Cell Reports
Päätekijät: Bohin, Natacha, Keeley, Theresa M., Carulli, Alexis J., Walker, Emily M., Carlson, Elizabeth A., Gao, Jie, Aifantis, Iannis, Siebel, Christian W., Rajala, Michael W., Myers, Martin G., Jones, Jennifer C., Brindley, Constance D., Dempsey, Peter J., Samuelson, Linda C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363878/
https://ncbi.nlm.nih.gov/pubmed/32531190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.05.010
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