Early modulation of macrophage ROS-PPARγ-NF-κB signalling by sonodynamic therapy attenuates neointimal hyperplasia in rabbits

Disruption of re-endothelialization and haemodynamic balance remains a critical side effect of drug-eluting stents (DES) for preventing intimal hyperplasia. Previously, we found that 5-aminolevulinic acid-mediated sonodynamic therapy (ALA-SDT) suppressed macrophage-mediated inflammation in atheroscl...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yao, Jianting, Zhao, Xuezhu, Tan, Fancheng, Cao, Xiaoru, Guo, Shuyuan, Li, Xiang, Huang, Zhen, Diabakte, Kamal, Wang, Lu, Liu, Mingyu, Shen, Zhaoqian, Li, Bicheng, Cao, Zhengyu, Sheng, Siqi, Lu, Minqiao, Cao, Yang, Jin, Hong, Zhang, Zhiguo, Tian, Ye
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363872/
https://ncbi.nlm.nih.gov/pubmed/32669704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68543-9
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