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The effects of PPARγ agonist rosiglitazone on neointimal hyperplasia in rabbit carotid anastomosis model

BACKGROUND: Neointimal hyperplasia involving smooth muscle cell (SMC) proliferation, migration and extracellular matrix (ECM) degradation is an important component of atherosclerosis. It develops as a response to vascular injury after balloon angioplasty and vascular graft placement. Matrix metallop...

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Detalhes bibliográficos
Main Authors: Guzeloglu, Mehmet, Reel, Buket, Atmaca, Soner, Bagrıyanık, Alper, Hazan, Eyup
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487767/
https://ncbi.nlm.nih.gov/pubmed/22716287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8090-7-57
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