Large-scale DNA-based phenotypic recording and deep learning enable highly accurate sequence-function mapping

Predicting effects of gene regulatory elements (GREs) is a longstanding challenge in biology. Machine learning may address this, but requires large datasets linking GREs to their quantitative function. However, experimental methods to generate such datasets are either application-specific or technic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Höllerer, Simon, Papaxanthos, Laetitia, Gumpinger, Anja Cathrin, Fischer, Katrin, Beisel, Christian, Borgwardt, Karsten, Benenson, Yaakov, Jeschek, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363850/
https://ncbi.nlm.nih.gov/pubmed/32669542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17222-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados