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Fungal Kti12 proteins display unusual linker regions and unique ATPase p-loops

Kti12 (Kluyveromyces lactis toxin insensitive 12) is an evolutionary highly conserved ATPase, crucial for the tRNA-modification activity of the eukaryotic Elongator complex. The protein consists of an N-terminal ATPase and a C-terminal tRNA-binding domain, which are connected by a flexible linker. T...

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Detalhes bibliográficos
Publicado no:Curr Genet
Main Authors: Krutyhołowa, Rościsław, Reinhardt-Tews, Annekathrin, Chramiec-Głąbik, Andrzej, Breunig, Karin D., Glatt, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363723/
https://ncbi.nlm.nih.gov/pubmed/32236652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-020-01070-2
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