Mechanisms of aortic carboxypeptidase-like protein secretion and identification of an intracellularly retained variant associated with Ehlers–Danlos syndrome

Aortic carboxypeptidase-like protein (ACLP) is a collagen-binding extracellular matrix protein that has important roles in wound healing and fibrosis. ACLP contains thrombospondin repeats, a collagen-binding discoidin domain, and a catalytically inactive metallocarboxypeptidase domain. Recently, mut...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Vishwanath, Neya, Monis, William J., Hoffmann, Gwendolyn A., Ramachandran, Bhavana, DiGiacomo, Vincent, Wong, Joyce Y., Smith, Michael L., Layne, Matthew D.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
Sujets:
Glycobiology and Extracellular Matrices
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363150/
https://ncbi.nlm.nih.gov/pubmed/32482891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013902
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