Apoptotic cells induce CD103 expression and immunoregulatory function in myeloid dendritic cell precursors through integrin α(v) and TGF-β activation

In the mammalian gut CD103+ve myeloid DCs are known to suppress inflammation threatened by luminal bacteria, but stimuli driving DC precursor maturation towards this beneficial phenotype are incompletely understood. We isolated CD11+ve DCs from mesenteric lymph nodes (MLNs) of healthy mice; CD103+ve...

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Udgivet i:PLoS One
Main Authors: Zhang, Ailiang, Paidassi, Helena, Lacy-Hulbert, Adam, Savill, John
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363096/
https://ncbi.nlm.nih.gov/pubmed/32667911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232307
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