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Somalier: rapid relatedness estimation for cancer and germline studies using efficient genome sketches
BACKGROUND: When interpreting sequencing data from multiple spatial or longitudinal biopsies, detecting sample mix-ups is essential, yet more difficult than in studies of germline variation. In most genomic studies of tumors, genetic variation is detected through pairwise comparisons of the tumor an...
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Udgivet i: | Genome Med |
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Main Authors: | , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
BioMed Central
2020
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7362544/ https://ncbi.nlm.nih.gov/pubmed/32664994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00761-2 |
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