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Proteomic analysis of the S. cerevisiae response to the anticancer ruthenium complex KP1019
Like platinum-based chemotherapeutics, the anticancer ruthenium complex indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)], or KP1019, damages DNA, induces apoptosis, and causes tumor regression in animal models. Unlike platinum-based drugs, KP1019 showed no dose-limiting toxicity in a pha...
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| Gepubliceerd in: | Metallomics |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7362344/ https://ncbi.nlm.nih.gov/pubmed/32329475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0mt00008f |
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