DNA Damage Response Checkpoint Activation Drives KP1019 Dependent Pre-Anaphase Cell Cycle Delay in S. cerevisiae

Careful regulation of the cell cycle is required for proper replication, cell division, and DNA repair. DNA damage–including that induced by many anticancer drugs–results in cell cycle delay or arrest, which can allow time for repair of DNA lesions. Although its molecular mechanism of action remains...

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Udgivet i:PLoS One
Main Authors: Bierle, Lindsey A., Reich, Kira L., Taylor, Braden E., Blatt, Eliot B., Middleton, Sydney M., Burke, Shawnecca D., Stultz, Laura K., Hanson, Pamela K., Partridge, Janet F., Miller, Mary E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572706/
https://ncbi.nlm.nih.gov/pubmed/26375390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138085
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