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Differential Regulation of Anaphase Promoting Complex/Cyclosome Substrates by the Spindle Assembly Checkpoint in Saccharomyces cerevisiae

The anaphase promoting complex (APC) targets proteins for degradation to promote progression through the cell cycle. Here we show that Clb5, an APC(Cdc20) substrate, is degraded when the spindle checkpoint is active, while other APC(Cdc20) substrates are stabilized, suggesting that APC(Cdc20) inhibi...

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書誌詳細
主要な著者: Keyes, Brice E., Yellman, Christopher M., Burke, Daniel J.
フォーマット: Artigo
言語:Inglês
出版事項: Genetics Society of America 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206106/
https://ncbi.nlm.nih.gov/pubmed/18202397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.083642
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