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Differential Regulation of Anaphase Promoting Complex/Cyclosome Substrates by the Spindle Assembly Checkpoint in Saccharomyces cerevisiae
The anaphase promoting complex (APC) targets proteins for degradation to promote progression through the cell cycle. Here we show that Clb5, an APC(Cdc20) substrate, is degraded when the spindle checkpoint is active, while other APC(Cdc20) substrates are stabilized, suggesting that APC(Cdc20) inhibi...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206106/ https://ncbi.nlm.nih.gov/pubmed/18202397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.083642 |
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