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Ganoderma lucidum Prevents Cisplatin-Induced Nephrotoxicity through Inhibition of Epidermal Growth Factor Receptor Signaling and Autophagy-Mediated Apoptosis

BACKGROUND: Cisplatin (cis-diaminedichloroplatinum, CDDP) is a broad-spectrum antineoplastic agent. However, CDDP has been blamed for its nephrotoxicity, which is the main dose-limiting adverse effect. Ganoderma lucidum (GL), a medicinal mushroom, has antioxidant and inflammatory activities. Therefo...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Mahran, Yasmen F., Hassan, Hanan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362286/
https://ncbi.nlm.nih.gov/pubmed/32695255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4932587
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