Holistic View on Cell Survival and DNA Damage: How Model-Based Data Analysis Supports Exploration of Dynamics in Biological Systems

In this work, a method is established to calibrate a model that describes the basic dynamics of DNA damage and repair. The model can be used to extend planning for radiotherapy and hyperthermia in order to include the biological effects. In contrast to “syntactic” models (e.g., describing molecular...

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Detalhes bibliográficos
Publicado no:Comput Math Methods Med
Main Authors: Weyland, Mathias S., Thumser-Henner, Pauline, Nytko, Katarzyna J., Rohrer Bley, Carla, Ulzega, Simone, Petri-Fink, Alke, Lattuada, Marco, Füchslin, Rudolf M., Scheidegger, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361897/
https://ncbi.nlm.nih.gov/pubmed/32695215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5972594
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