Pravastatin attenuates atherosclerosis after myocardial infarction by inhibiting inflammatory Ly6C(high) monocytosis in apolipoprotein E knockout mice

OBJECTIVE: To evaluate the protective effect of pravastatin on atherosclerotic development and inflammatory monocyte subset in atherosclerotic apolipoprotein E (ApoE)(−/−) mice after myocardial infarction (MI). METHODS: Male ApoE(−/−) mice (8 weeks old) were fed a high-fat diet for 14 weeks througho...

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Detalhes bibliográficos
Publicado no:J Int Med Res
Main Authors: Chen, Yufei, Zhang, Hongqi, Hu, Liang, Shi, Haiming, Liu, Xiaojin, Jia, Jianguo, Sun, Shengjia, Ou, Yang, Luo, Xinping, Zhou, Guomin, Shen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Pre-Clinical Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361503/
https://ncbi.nlm.nih.gov/pubmed/32662710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060520932816
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