Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway

The alarm cytokine interleukin‐1β (IL‐1β) is a potent activator of the inflammatory cascade following pathogen recognition. IL‐1β production typically requires two signals: first, priming by recognition of pathogen‐associated molecular patterns leads to the production of immature pro‐IL‐1β; subseque...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Ipseiz, Natacha, Pickering, Robert J, Rosas, Marcela, Tyrrell, Victoria J, Davies, Luke C, Orr, Selinda J, Czubala, Magdalena A, Fathalla, Dina, Robertson, Avril AB, Bryant, Clare E, O'Donnell, Valerie, Taylor, Philip R
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360975/
https://ncbi.nlm.nih.gov/pubmed/32484988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103454
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