Toll-Like Receptor 4 (TLR4)/Opioid Receptor Pathway Crosstalk and Impact on Opioid Analgesia, Immune Function, and Gastrointestinal Motility

Toll-like receptor 4 (TLR4) recognizes exogenous pathogen-associated molecular patterns (PAMPs) and endogenous danger-associated molecular patterns (DAMPs) and initiates the innate immune response. Opioid receptors (μ, δ, and κ) activate inhibitory G-proteins and relieve pain. This review summarizes...

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Pubblicato in:Front Immunol
Autori principali: Zhang, Peng, Yang, Meirong, Chen, Chunhua, Liu, Liu, Wei, Xinchuan, Zeng, Si
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360813/
https://ncbi.nlm.nih.gov/pubmed/32733481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01455
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