IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules

It is unclear whether the establishment of apical–basal cell polarity during the generation of epithelial lumens requires molecules acting at the plasma membrane/actin interface. Here, we show that the I-BAR-containing IRSp53 protein controls lumen formation and the positioning of the polarity deter...

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Publicat a:Nat Commun
Autors principals: Bisi, Sara, Marchesi, Stefano, Rizvi, Abrar, Carra, Davide, Beznoussenko, Galina V., Ferrara, Ines, Deflorian, Gianluca, Mironov, Alexander, Bertalot, Giovanni, Pisati, Federica, Oldani, Amanda, Cattaneo, Angela, Saberamoli, Ghazaleh, Pece, Salvatore, Viale, Giuseppe, Bachi, Angela, Tripodo, Claudio, Scita, Giorgio, Disanza, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360740/
https://ncbi.nlm.nih.gov/pubmed/32665580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17091-x
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