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Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia
Acute myeloid leukemia (AML) is characterised by a series of genetic and epigenetic alterations that result in deregulation of transcriptional networks. One understudied source of transcriptional regulators are transposable elements (TEs), whose aberrant usage could contribute to oncogenic transcrip...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7360734/ https://ncbi.nlm.nih.gov/pubmed/32665538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17206-4 |
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