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Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia

Acute myeloid leukemia (AML) is characterised by a series of genetic and epigenetic alterations that result in deregulation of transcriptional networks. One understudied source of transcriptional regulators are transposable elements (TEs), whose aberrant usage could contribute to oncogenic transcrip...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Deniz, Özgen, Ahmed, Mamataz, Todd, Christopher D., Rio-Machin, Ana, Dawson, Mark A., Branco, Miguel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360734/
https://ncbi.nlm.nih.gov/pubmed/32665538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17206-4
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