GBA3: a polymorphic pseudogene in humans that experienced repeated gene loss during mammalian evolution

The gene encoding the cytosolic β-glucosidase GBA3 shows pseudogenization due to a truncated allele (rs358231) that is polymorphic in humans. Since this enzyme is involved in the transformation of many plant β-glycosides, this particular case of gene loss may have been influenced by dietary adaptati...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lopes-Marques, Monica, Serrano, Catarina, Cardoso, Ana R., Salazar, Renato, Seixas, Susana, Amorim, António, Azevedo, Luisa, Prata, Maria J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360587/
https://ncbi.nlm.nih.gov/pubmed/32665690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68106-y
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