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Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response

Known examples of ancient identical-by-descent genetic variants being shared between evolutionarily related species, known as trans-species polymorphisms (TSPs), result from counterbalancing selective forces acting on target genes to confer resistance against infectious agents. To date, putative TSP...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Azevedo, Luisa, Serrano, Catarina, Amorim, Antonio, Cooper, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559023/
https://ncbi.nlm.nih.gov/pubmed/26337052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0043-1
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