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Golgi compartments enable controlled biomolecular assembly using promiscuous enzymes
The synthesis of eukaryotic glycans – branched sugar oligomers attached to cell-surface proteins and lipids – is organized like a factory assembly line. Specific enzymes within successive compartments of the Golgi apparatus determine where new monomer building blocks are linked to the growing oligom...
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| Опубликовано в: : | eLife |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7360365/ https://ncbi.nlm.nih.gov/pubmed/32597757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49573 |
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