The HCMV Assembly Compartment is a dynamic Golgi-derived MTOC that controls nuclear rotation and virus spread

Human Cytomegalovirus (HCMV), a leading cause of congenital birth defects, forms an unusual cytoplasmic virion maturation site termed the “Assembly Compartment” (AC). Here, we show that the AC also acts as a microtubule-organizing center (MTOC) wherein centrosome activity is suppressed and Golgi-bas...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Procter, Dean J., Banerjee, Avik, Nukui, Masatoshi, Kruse, Kevin, Gaponenko, Vadim, Murphy, Eain A., Komarova, Yulia, Walsh, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896778/
https://ncbi.nlm.nih.gov/pubmed/29634939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.03.010
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