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Experimental and Computational Characterization of Oxidized and Reduced Protegrin Pores in Lipid Bilayers

Protegrin-1 (PG-1), an 18-residue β-hairpin stabilized by two disulfide bonds, is a member of a family of powerful antimicrobial peptides which are believed to act through membrane permeabilization. Here we used a combination of experimental and computational approaches to characterize possible stru...

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Veröffentlicht in:J Membr Biol
Hauptverfasser: Rodnin, Mykola V., Vasquez-Montes, Victor, Nepal, Binod, Ladokhin, Alexey S., Lazaridis, Themis
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360341/
https://ncbi.nlm.nih.gov/pubmed/32500172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-020-00124-3
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