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Reliability of digital PCR in detecting KRAS mutation in colorectal cancer using plasma sample: A systematic review and meta-analysis

BACKGROUND: Test on the KRAS somatic mutation status is necessary before cetuximab and panitumumab treatments are given to colorectal cancer patients. Metastatic colorectal cancer patients sometimes lack tumor tissue samples, and the testing of KRAS mutation in plasma samples requires highly sensiti...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Ye, Peng, Cai, Peiling, Xie, Jing, Zhang, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360253/
https://ncbi.nlm.nih.gov/pubmed/32664155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000021171
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