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Locked Nucleic Acid and TaqMan Probes to Detect KRAS Mutations by Droplet Digital PCR in Colorectal Carcinoma Formalin Fixed Paraffin Embedded Tissue Samples

BACKGROUND: Metastatic colorectal carcinoma (CRC) tumors with KRAS mutations in exon 2, codons 12 and 13, do not benefit from anti-epidermal growth factor receptor (EGFR) antibody therapy. Current best practice recommends that KRAS mutation analysis be included in patients with CRC as a prerequisite...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chapman, B., Brown, A., Cooper, S., Yang, W., Karlin-Neumann, G., Binder, S., Sullivan, D.C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Association of Biomolecular Resource Facilities 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162247/
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