Human B cell clonal expansion and convergent antibody responses to SARS CoV-2

During virus infection B cells are critical for the production of antibodies and protective immunity. Here we show that the human B cell compartment in patients with diagnostically confirmed SARS-CoV-2 and clinical COVID-19 is rapidly altered with the early recruitment of B cells expressing a limite...

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Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: Nielsen, Sandra C. A., Yang, Fan, Jackson, Katherine J. L., Hoh, Ramona A., Röltgen, Katharina, Stevens, Bryan, Lee, Ji-Yeun, Rustagi, Arjun, Rogers, Angela J., Powell, Abigail E., Najeeb, Javaria, Otrelo-Cardoso, Ana R., Yost, Kathryn E., Daniel, Bence, Chang, Howard Y., Satpathy, Ansuman T., Jardetzky, Theodore S., Kim, Peter S., Wang, Taia T., Pinsky, Benjamin A., Blish, Catherine A., Boyd, Scott D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359515/
https://ncbi.nlm.nih.gov/pubmed/32676593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.08.194456
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