Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells

BACKGROUND: Currently, the diagnosis and treatment of neuroblastomas—the most frequent solid tumors in children—exploit the norepinephrine transporter (hNET) via radiolabeled norepinephrine analogs. We aim to develop a nanomedicine-based strategy towards precision therapy by targeting hNET cell-surf...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Nanobiotechnology
Prif Awduron: Haddad, Yazan, Charousova, Marketa, Zivotska, Hana, Splichal, Zbynek, Merlos Rodrigo, Miguel Angel, Michalkova, Hana, Krizkova, Sona, Tesarova, Barbora, Richtera, Lukas, Vitek, Petr, Stokowa-Soltys, Kamila, Hynek, David, Milosavljevic, Vedran, Rex, Simona, Heger, Zbynek
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359476/
https://ncbi.nlm.nih.gov/pubmed/32660596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00654-x
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