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The Zinc-Schiff Base-Novicidin Complex as a Potential Prostate Cancer Therapy

Prostate cancer cells control energy metabolism by chelating intracellular zinc. Thus, zinc delivery has been a popular therapeutic approach for prostate cancer. Here, we propose the use of the membrane-penetrating peptide Novicidin connected to zinc-Schiff base as a carrier vehicle for the delivery...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Milosavljevic, Vedran, Haddad, Yazan, Merlos Rodrigo, Miguel Angel, Moulick, Amitava, Polanska, Hana, Hynek, David, Heger, Zbynek, Kopel, Pavel, Adam, Vojtech
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058503/
https://ncbi.nlm.nih.gov/pubmed/27727290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163983
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