Detection of low-level HCV variants in DAA treated patients: comparison amongst three different NGS data analysis protocols

BACKGROUND: Notwithstanding the efforts of direct-acting antivirals (DAAs) for the treatment of chronically infected hepatitis C virus (HCV) patients, concerns exist regarding the emergence of resistance-associated substitutions (RAS) related to therapy failure. Sanger sequencing is still the refere...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Caputo, Valeria, Diotti, Roberta Antonia, Boeri, Enzo, Hasson, Hamid, Sampaolo, Michela, Criscuolo, Elena, Bagaglio, Sabrina, Messina, Emanuela, Uberti-Foppa, Caterina, Castelli, Matteo, Burioni, Roberto, Mancini, Nicasio, Clementi, Massimo, Clementi, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359454/
https://ncbi.nlm.nih.gov/pubmed/32660499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01381-3
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