Natural polymorphisms in the resistance associated sites of HCV-G1 NS5B domain and correlation with geographic origin of HCV isolates

BACKGROUND: We evaluated the frequency of naturally occurring resistance associated substitutions (RASs) and their characteristic of polymorphic or non-polymorphic amino acid change to direct acting antivirals (DAAs) in NS5b HCV subtypes 1a and 1b according to different geographic origin of isolates...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Virol J
Main Authors: Bagaglio, Sabrina, Uberti-Foppa, Caterina, Olgiati, Alessandro, Messina, Emanuela, Hasson, Hamid, Ferri, Camilla, Morsica, Giulia
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145338/
https://ncbi.nlm.nih.gov/pubmed/30227876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-018-1054-z
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