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Immunohistochemical detection of p53 and pp53 Ser(392) in canine hemangiomas and hemangiosarcomas located in the skin

BACKGROUND: p53 protein is essential for the regulation of cell proliferation. Aberrant accumulation of it usually occurs in cutaneous malignancies. Mutant p53 is detected by immunohistochemistry because it is more stable than the wild-type p53. However, post-translational modifications of p53 in re...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: García-Iglesias, María José, Cuevas-Higuera, Jose Luis, Bastida-Sáenz, Ana, de Garnica-García, María Gracia, Polledo, Laura, Perero, Paula, González-Fernández, Jorge, Fernández-Martínez, Beatriz, Pérez-Martínez, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359283/
https://ncbi.nlm.nih.gov/pubmed/32660487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02457-6
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