Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organization in stress-induced senescence of MSCs

BACKGROUND: Stem cell senescence has been proposed as one of the major drivers of aging, and MSC senescence contributes to aging-related diseases. Activation of mTORC1 pathway and heterochromatin organization have been characterized as two characteristics of senescent cells; however, whether mTORC1...

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Detaylı Bibliyografya
Yayımlandı:Stem Cell Res Ther
Asıl Yazarlar: Liu, Hailong, Huang, Biao, Xue, Shaolong, U, Kin Pong, Tsang, Lai Ling, Zhang, Xiaohu, Li, Gang, Jiang, Xiaohua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359252/
https://ncbi.nlm.nih.gov/pubmed/32660632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01798-1
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