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Interaction of DNA Topoisomerase 1 with DNA Intermediates and Proteins of Base Excision Repair

The interaction of human recombinant DNA topoisomerase 1 (Top1) with linear and circular DNA structures containing a nick or short gap but lacking a specific Top1 recognition site was studied. The effect of key excision repair proteins on formation of the Top1 covalent adduct with the DNA repair int...

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Bibliographic Details
Published in:Biochemistry (Mosc)
Main Authors: Lebedeva, N. A., Rechkunova, N. I., Agama, K., Pommier, Y., Lavrik, O. I.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359218/
https://ncbi.nlm.nih.gov/pubmed/19916945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1134/s0006297909110157
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